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This review summarises recent advances in the understanding of diabetic gastroparesis, with an emphasis on the current therapies that influence GE, and the bidirectional relationship between glycaemic control and GE.

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very low certainty of evidence) relative to SGLT2 inhibitor or GLP-1 RA monotherapy

In conclusion, the paper provides evidence that the reduction of GLP-1+ cells is a general feature of ileal and colonic inflammation in mice and humans and is likely due to altered epithelial differentiation driven by changes in cellular metabolism, particularly mitochondrial dysfunction.

Read our IVY RX review for GLP-1 telemedicine with semaglutide and tirzepatide