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51,52 In LR, ER stress also affects leptin signaling, blocking the JAK2/STAT3 pathway triggered by leptin present in POMC neurons, potentially contributing to metabolic disturbances in the peripheral tissues of obese phenotypes (Fig

These health conditions result from delayed stomach emptying and bile stasis, which are documented side effects of GLP-1 receptor agonists

Statements Author contributions Conceptualization: MH., MS, and BC

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For example, in people with OCD, the increase in serotonin can help reduce the intrusive thoughts and repetitive behaviors that characterize the disorder
