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The only comparator was placebo, and we already knew that stopping these medications would result in weight regain, Albanese says

The fertility implications of tirzepatide are also worth understanding, as improved metabolic health can increase fertility in women with PCOS or obesity-related anovulation

Schmidt PT, Hartmann B, Bregenholt S et al (2000) Deficiency of the intestinal growth factor, glucagon-like peptide 2, in the colon of SCID mice with inflammatory bowel disease induced by transplantation of CD4+ T cells

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They also showed improvement in various vascular markers such as endothelial glycocalyx thickness, global left ventricular strain, and myocardial work index