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Geniposide and its iridoid analogs exhibit antinociception by acting at the spinal GLP-1 receptors

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Future studies are needed to further clarify the clinical advantages of GIPR/GLP-1R dual agonists beyond weight loss

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Understanding what happens when you stop is crucial

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In a related development, Sun Pharma had already received DCGI approval in December 2025 to manufacture and market semaglutide injection for adults with insufficiently controlled type 2 diabetes mellitus, as an adjunct to diet and exercise

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These protective effects extend beyond weight loss and likely involve semaglutide's direct action on heart and blood vessel cells

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