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Furthermore, some of these drugsparticularly insulin and sulfonylurealead to undesired risks including hypoglycemia and weight gain [5]

Georgescu EF, Ionescu R, Niculescu M, et al

7.9% reported serious side effects, with one death 12 of the 152 participants (7.9%) in one study reported serious adverse side effects compared to the placebo group, 18 of 152 participants (11.8%)

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Pubmed Central PMCID: 3594872)