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Compounded GLP-1s is contraindicated in patients with a family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

13,14 In these patients, the potential of GLP-1 agonists not only can deliver improvement for the targeted conditions, but can reduce comorbidities, such as obesity, dyslipidemia, and cardiovascular disease

44 Liraglutide reduces oxidative stress by reducing apoptosis and normalizing some of the mitochondrial dynamic imbalances

However, because childhood asthma is largely driven by type 2 immune pathways and differs pathophysiologically from adult asthma, it was important to assess whether similar associations could be observed in pediatric populations using real-world data. The results of the study found that for those young people with difficult to control asthma who find sustained weight-loss difficult, GLP-1s may be a good option