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Both participants and study staff were blinded to treatment assignment

Tirzepatide did not impact metabolic adaptation during weight loss in people with obesity

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Subgroup analyses (duration) of the effects of GLP-1 receptor agonists on the risk of overall respiratory disease

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23 The SURMOUNT-1 trial revealed a mean percent change in BW over placebo of 15%, 19.5% and 20.9% in those receiving tirzepatide at doses of 5, 10, and 15 mg, respectively
