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A review of 30 randomized controlled trials that included 1,736 people with type 2 diabetes or non-alcoholic fatty liver disease found that treatment with GLP-1 agonists significantly reduced both visceral and liver fat

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Power calculations suggest that previous studies would have had limited power to detect an effect size similar to that identified in our study (Supplementary Table 23), and also differed in terms of drug type, disease cohort and analytical choices

In clinical trials, 89% of participants taking Zepbound at the 5mg dose achieved at least 5% body weight loss, while 96% of those taking the 10mg and 15mg doses reached this threshold

Dosing titrated by your provider to ease side effects Side effects handled reactively, if at all

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