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However, he acknowledged that several large database studies have failed to consistently reproduce the same association (Figure 2)

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The triple mechanism suggests that discontinuation effects could be even more pronounced than with tirzepatide
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J., Sandoval, D., & DAlessio, D

Thus, epidemiological trends are not isolated observations but manifestations of molecular pathways, including genetic polymorphisms, inflammatory signaling, and altered lipid handling, which predispose populations to differential risks of MASLD and T2DM

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