glp 1 agonist and pregnancy How safe are GLP-1R agonists in early pregnancy? Navigating GLP-1 and Pregnancy: Insights,
Description
Nevertheless, our findings should be interpreted in the context of several limitations

Lancet 398(10313):18111824

The addition of lixisenatide to standard therapy did not significantly alter the rates of CV events or hospitalizations in high-risk patients, although it did result in modest but significant reductions in A1c, weight, and systolic BP compared to standard therapy
In addition, patients frequently report that the reductions in substance use cravings occur immediately when they increase their dose and sometimes report that cravings return weekly as they reach day 5 or 6 before taking their next injection on day 7

Nathan D

2021, doi: 10.1056/NEJMoa2032183