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Description
A 2023 New England Journal of Medicine trial found that adolescents aged 1217 with severe obesity who received semaglutide achieved approximately 16% weight loss over 68 weeks, compared to 2% in the placebo group

48 Wadden TA, Bailey TS, Billings LK, Davies M, Frias JP, Koroleva A, et alEffect of subcutaneous semaglutide vs placebo as an adjunct to intensive behavioral therapy on body weight in adults with overweight or obesity: The STEP 3 randomized clinical trial

doi: 10.1194/jlr.M012203

Genetic factors may also play a role, as some people inherit a wider-than-average hiatal opening where the esophagus connects to the stomach

Do women lose more weight with semaglutide

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