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Type 2 diabetes GLP-1 and GIP receptor activation both improve insulin secretion and blood sugar control

dehydration can contribute to cramps, dizziness, and fatigue

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This agent may lead to earlier initiation of GLP-1RA therapy in the type 2 diabetes continuum of care, and represents a valuable treatment option for patients with a preference for oral therapy

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GIPGLP-12GLP-112 GIPGLP-1212 GLP-1 GLP-1GLP-11 GLP-1GIP12 GIPGLP-1 GIPGLP-12 2 GIPGLP-1 GIP39GLP-1 1 GLP-1 GLP-1-1GLP-1 GLP-1 GLP-1L1015 GLP-1DPP-4-4 GLP-1cAMPAMPcAMP GLP-1 GLP-1 GLP-1 GIP1 GIPGIP GIP GIPGLP-1K 2GIPGIPGIP GIP GIPGIP GIP GIP GIP 2GIPHbA1cGLP-1GIP GIPGIP 872Cmax 51 GIPGLP-1cAMPcAMPAPKAEpac2 GLP-1 GLP-1 SURPASS SURPASSHbA1cA1c SURPASS SURPASS1532GLP-1 5mg10mg15mg3SURPASS J-monoSURPASS J-combo HbA1c SURPASS-21mg15mgHbA1c2.5%1mg1.9% 15mg1112kgGLP-1 SURPASS HbA1cGIPGIP SU GLP-1 MTCMTC2MEN2 1 1 2.5mg45mg10mg15mg 2.5mg14 5mg4 10mg 15mg 3 4964 1 GIPGLP-122 GLP-1 GLP-1GLP-1GIPSURPASS-2HbA1c 2 1 496 412 References NAUCK, Michael A