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Individuals with obesity have decreased overall levels of GLP-1-expressing EECs, a deficit that is more pronounced in individuals with obesity and type 2 diabetes (Osinski et al., 2021)

Tirzepatide, a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, affects gastric emptying by slowing the movement of food through the stomach

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It can also be used to treat overweight adults who have at least one weight-related medical condition, such as high cholesterol or high blood pressure