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Some patients have genetic markers suggesting they'll respond better to combined therapy (semaglutide plus tirzepatide) rather than semaglutide alone

Factors secreted by the hypothalamus, the pituitary and adrenal glands, such as corticotrophin-releasing hormone, adrenocorticotropic hormone and glucocorticoids, can influence both immune and neuroendocrine responses

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Benefits of GLP-1 Agonists in MASH Histologic Improvements Studies have shown that treatment with GLP-1 agonists can lead to a reduction in liver inflammation and fibrosis, and hence result in an improvement in the overall structure of liver tissue1

Microdosing or starting with a l ower dose may help to prevent gastrointestinal side effects
