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Science 348 , 453457 (2015)

In the UK, the QRISK calculator algorithm has been derived and validated in 2.3 million people to estimate CVD risk in different ethnic groups and unlike other calculators, it counts South Asian origins as an additional risk factor

Several mechanisms may contribute to tiredness on tirzepatide

NICE technology appraisal TA875 (2023) recommends semaglutide 2.4 mg (Wegovy) as an adjunct to a reduced-calorie diet and increased physical activity for adults with a BMI of 35 kg/m or above (or 3034.9 kg/m in certain circumstances) alongside at least one weight-related comorbidity, when initiated within specialist weight management services
