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Whether berberine can substitute for metformin in any individual case is a clinical decision requiring physician input, not a one-size-fits-all answer

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It lands on Schedule IV due to its phentermine component and has warnings about use in the setting of cardiovascular disease, in addition to concerns about topiramate side effects that include drowsiness, changes in sensation, and kidney stones

Ozempic is a drug for type 2 diabetes that also helps people lose weight by acting like the hormone GLP-1

The SURPASS clinical trials included patients with stable cardiovascular disease, though those with unstable or severe cardiovascular conditions were typically excluded

This could lead to inadequate pain control or a perceived need for higher doses, which then introduces greater risks associated with hydrocodone itself