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GLP-1 and GIP are incretin hormones that stimulate insulin secretion after an oral glucose load by binding GLP-1R, but both are rapidly inactivated by the enzyme dipeptidyl peptidase-4 (DPP-4)
For patients without insurance coverage for brand-name GLP-1 medications, compounded semaglutide provides access to the same molecule at a fraction of the cost
Faster absorption than oral GLP-1 Direct application leads to quicker effects than oral forms
Sohn M, Dietrich JW, Nauck MA, et al
Le Glau L, Rouault C, Osinski C, Prifti E, Soula HA, Debdat J, et al
