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And you are telling us this story that I think in another 12 years, 50% of all Americans will have obesity

These findings collectively indicate that the taste-modulating effects of incretin therapies arise from integrated gut-brain mechanisms that reshape reward processing and conditioned preferences

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This rebound effect is driven by complex physiological adaptations, such as increased appetite, reduced energy expenditure, and hormonal changes that favor weight restoration [12,13]

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