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doi: 10.1017/S0007114508944135

Also, the limited size of certain subgroups of patients impacted results

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For example, some GLP-1R agonists primarily activate the insulin secretion signaling pathway, whereas others focus more on promoting insulin sensitivity or inhibiting glucagon secretion (Deganutti et al., 2022)
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Conclusion T2DM is a progressive disease and treatment intensification is often required to achieve and maintain glycemic control [1, 2]
