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Peer review Peer review information Nature Medicine thanks Christiana Kartsonaki, Naveed Sattar and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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As before, these side effects are likely to disappear on their own
[DOI] [PubMed] [Google Scholar] 65.Efficacy and safety of novel twincretin tirzepatide a dual GIP and GLP-1 receptor agonist in the management of type-2 diabetes: a Cochrane meta-analysis
Shivappa N, Swift C, Noone J, Du S, Radin M, Gamble C

The SEMALEAN study followed 106 adults with obesity (mean BMI 46, mean age 52, roughly half meeting sarcopenic obesity criteria at baseline) on max-dose semaglutide for 12 months, with DXA and handgrip dynamometry at baseline, seven months, and twelve months
