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The resulting average body weight loss of 3.7% was highly significant compared to the placebo group
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The Medicines and Healthcare products Regulatory Agency (MHRA) and manufacturers' Summaries of Product Characteristics (SmPCs) consistently advise against using GLP-1 receptor agonists whilst breastfeeding due to insufficient data on excretion into human breast milk and potential effects on nursing infants
Endosomal GPCR signaling turned off by negative feedback actions of PKA and v-ATPase
