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With DPP4 inhibitors as a comparator previously shown to have neutral effects on cognition [10, 11], the present study demonstrates that SGLT2 inhibitors may reduce dementia risk in adults with type 2 diabetes aged 60 years, but the association between the study GLP1 receptor agonists and dementia risk reduction is less certain

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In a study from Cuba, Vilar-Gomez et al 11 reported that of 29 patients who managed to lose at least 10% of their body weight, 26 (90%) had MASH resolution and 13 (45%) had fibrosis regression

In vivo , administration of metformin resulted in a decrease in testosterone secretion, however, this effect was reversed when metformin administration was stopped (61)

doi: 10.1530/joe-20-0277 40 KaramaliMEghbalpourSRajabiSJamilianMBahmaniFTajabadi-EbrahimiMet al

In a trial testing liraglutide in patients with type 2 diabetes, 28% more women than men reported adverse effects of the treatment
