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Glucagon-like peptide-1 (GLP-1) receptor agonists represent a class of medications that mimic the action of the naturally occurring incretin hormone GLP-1

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Altogether, clinical trials in phase 3 that applied semaglutide in monotherapy and combined with other antidiabetic drugs yielded similar results

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This review examines the neuroprotective potential and metabolic effects of GLP-1 RAs in PD, with particular emphasis on their impact on weight regulation, underlying mechanisms, clinical outcomes, and therapeutic prospects