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Despite the contradictory data regarding kidney outcomes, two surrogate outcomes benefit the most from combined therapy: the decline in eGFR slope and the reduction in urinary albumin-to-creatinine ratio

Dehydration is a leading cause of muscle irritability

Many of the patients who have experienced blindness after taking Ozempic have said that they wish they had been told that this could occur

It also helps to slow gastric emptying and inhibit inappropriate post-meal glucagon release

Furthermore, combining GLP1R agonism with standard-of-care ARSI decreased proliferation of CRPC cells more than ARSI alone

These findings suggest that tirzepatide has a positive effect on reducing fat in the liver and the amount of fat in the belly compared to insulin degludec