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Bowel obstruction Small increases in resting heart rate Thyroid C-cell tumors observed in animal studies Dizziness or lightheadedness Dry mouth or increased thirst Vision changes Dehydration related to excessive vomiting or diarrhea Temporary hair shedding during rapid weight reduction Severe allergic reactions, including swelling of the face or throat or difficulty breathing, require immediate medical attention

Causation is harder to prove

Adipocyte-specific deletion of Tcf7l2 induces dysregulated lipid metabolism and impairs glucose tolerance in mice

* There were no events of acute renal failure identified by the Medical Dictionary for Regulatory Activities terminology search in either of the treatment groups

Another issue is the practice of prescribing medications based on patient surveys, without direct contact with a medical professional