origin of glp 1 Glucagon-like peptide (GLP-1) Glucagon-like peptide-1 - Wikipedia

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Systemic and intracerebroventricular administration of exendin-4 or even native GLP-1 in male rats increases HRs up to 600 bpm (nearly double rat resting HR) and blood pressure for several hours postadministration (28, 130, 131)

The dose is adjusted based on basal blood glucose level every three days (Table 1)

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