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Topiramate modulates GABA receptors and voltage-gated ion channels

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These hormones interact with receptors in areas like the pancreas and brain, prompting the pancreas to release more insulin after meals and helping to lower blood sugar levels in people with type 2 diabetes

Weight Loss Efficacy: What the Trials Show The most reliable data comes from the manufacturers pivotal trials, which are large, randomized, placebo-controlled and FDA-reviewed