why is retatrutide better than ozempic vs Ozempic: the Weight Loss Gap So Large Retatrutide Promises Big Weight Loss,

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Nevertheless, even the most effective marketed incretin, the GLP-1/GIP dual agonist tirzepatide, produces a maximum HbA1c reduction of ~2.6%, with fewer than half of participants in the SURPASS trials reaching normoglycemia (HbA1c 10%), vehicle-treated animals lost ~40% of body weight over 3 months, consistent with prior reports showing comparable reductions from ~40 g at week 10 to ~25 g by week 20 19

The precise step sizes and timings varied by protocol arm

Stimulant laxatives may be used judiciously under medical supervision when needed

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