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It means moving at a pace where you can still hold a conversation, but you'd rather not

The SUMMIT trial demonstrated that treatment with tirzepatide reduced the risk of a composite of cardiovascular-related deaths or worsening heart failure, compared with placebo, and improved the health of patients with heart failure with preserved ejection fraction and obesity [147]

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In November 2022, dulaglutide was indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients 10 years of age with type 2 diabetes mellitus

Future research must focus on developing precision medicine strategies, expanding indications through rigorous trials, and creating accessible and affordable solutions to combat the ever-increasing global burden of CVD and related metabolic disorders

Twelve weeks of semaglutide in patients with obesity and type 2 diabetes produced a significant reduction in vastus lateralis cross-sectional area on ultrasound and yet maximum voluntary contraction (knee extension) and hand-grip strength were both unchanged