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Further, our findings may not be generalisable to youth with severe hyperglycaemia or those on chronic treatment and, due to limitations in sample size, we were only able to explore potential mediators of metformin response

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Unknowns (the big ones) Long-term safety: The longest trial data we have is 68 weeks

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Attempts to identify specific genes which might be implicated in the risk of AN have been less successful, although more recent genome-wide association studies have shown genetic correlations between AN and other psychiatric disorders

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Summary: Weight loss plateaus with Wegovy commonly occur due to metabolic adaptation, dietary adherence changes, fluid retention, underlying medical conditions, or medication interactions, rather than treatment failure

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Blood concentration of glucose, haematocrit level, pulse rate and blood pressure are measured at 30-min intervals for up to 3 h after the ingestion

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This specialized array combines distinct incretin receptor agonists within a single layout

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