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Editors note: This story was updated with comment by Eli Lilly.

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A collaborative discussion between patient and provider can determine the most appropriate course of action, which may include further diagnostic evaluation, treatment of underlying contributing factors, symptomatic management of RLS, or consideration of alternative diabetes or weight management therapies if symptoms are severe and refractory to other interventions

The publication of oral GLP-1 data and ultra-long-acting formulations addresses patient preference and adherence challenges, while higher-dose semaglutide results demonstrate that greater efficacy is achievable without compromising safety

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