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Safety and Side Effects While the benefits of Semaglutide and CKD are clear, the drug does have side effects

Oral thrush appears as white patches on the tongue, inner cheeks, or throat, often accompanied by soreness

In clinical weight loss studies, tirzepatide has generally produced greater average weight loss than semaglutide at studied therapeutic doses

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Adequate water intake directly supports saliva production , helps flush food debris and bacteria, and dilutes acid in the oral environment

If symptoms become intolerable, dose reduction or temporarily pausing escalation may be necessary