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1 The two dominant incretins are glucagon-like peptide-1 (GLP-1), secreted by enteroendocrine L cells (located in the ileum and colon), and glucose-dependent insulinotropic peptide (GIP), secreted by K cells (located mainly in the duodenum)
The choice often comes down to personal health history, goals, and access

Plateaus are also more common during the luteal phase, perimenopause, and periods of high stress

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