glp-1 weight loss explained receptor agonists Myths & Facts: GLP-1 Drugs

Weight loss typically accelerates as doses increase during the titration period

Hepatology 2018;67:328-357

25 , 26 In head-to-head RCTs, GLP-1 RAs that induce greater weight loss are also associated with larger BP reductions, 27 , 28 supporting a meaningful contribution of weight-mediated mechanisms to their antihypertensive effect

Moreover, we assessed overall risk of bias for each trial solely for the primary outcome of change in HbA 1c

This is critical even if you choose to exclude weight management GLP-1s from coverage

Avoiding trans fats and limiting deep-fried or overly processed foods is more important than cutting fat completely