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But clinical trial averages don't predict your personal outcome, and results from FDA-approved formulations in controlled trials don't certify identical performance from a compounded formulation

Food and Drug Administration (FDA) website
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Given the observed increased risk of colorectal cancer among patients receiving GLP-1 receptor agonists, clinicians should approach long-term prescribing of these agents with careful consideration, particularly in individuals with additional risk factors for colorectal cancer, such as a family history, obesity, inflammatory bowel disease, or long-standing type 2 diabetes

(2021) examined the contribution of the LDTg to GLP-1Rmediated suppression of cocaine seeking