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Description
GLP-1 triggers the release of insulin from your pancreas

On the one hand, secondary BAs activate Takeda G protein-coupled receptor 5 (TGR5) on intestinal L cells to stimulate GLP-1 secretion (70, 71)

For patients with contraindications to GLP-1 receptor agonists, numerous effective alternatives exist for managing type 2 diabetes and obesity

(2018) 97:e11946

Strategies to Prevent Weight Regain on Continuous Therapy The most effective approach is maintaining uninterrupted GLP-1 therapy while you build sustainable eating habits and movement patterns

& Nauck, M
