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reported substituted quinoxalines ( 14 ) discovered from an extensive screening campaign with 500 000-membered library (Figure 3)

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The dominant impurities present at this include peptides with: Residue deletions Partial deprotections Sequence isomers Charge variants Aggregates Residue deletion peptides, partial deprotections, and sequence isomers usually represent the significant classes of impurities immediately after solid-phase peptide synthesis (SPPS) or the "crude" stage

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