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A: Thermogenics are substances that boost metabolism and increase calorie burning by promoting heat generation in the body

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Insulin resistance and chronic hyperglycemia cause a cascade of pathological events in the brain, including neuroinflammation, impaired neurotransmitter systems and energy metabolism, oxidative stress, and vascular pathologies that ultimately lead to neurodegeneration, loss of synaptic plasticity, brain aging, cognitive impairment, and dementia

In this article, we explore the role and therapeutic potential of these well-established obesity drug targets

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