how safe is glp-1 Your guide to side effects How Effective and Safe Are

There are no specific timing requirements for coordinating administration of these medications

The ADA recommends against using non-FDA-approved compounded GLP-1 and dual GIP/GLP-1 receptor agonist products due to safety, quality and effectiveness concerns and uncertainty about their content, Joshua J

So, safety's a gamble if not done right

In adults, registries have not shown major safety signals

Thus, apart from modifying the specificity of drugs to receptors, enhancing their affinity can significantly improve the weight reduction outcomes of GLP-1RA drugs

More specifically, it was more effective in preventing antipsychotic induced weight gain in first episode patients than in chronic patients who have already gained weight implying that it shows more efficacy in preventing weight gain before the onset of significant insulin resistance (19)