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It's important to avoid eating too little while on GLP-1

both hypokalemia (low potassium) and hyperkalemia (high potassium) can trigger dangerous heart rhythm disturbances

Although it is challenging to contextualize milk exposure this far postpartum, breast milk appeared to be a significant portion of the infant diet for most dyads, with minimal formula exposure

This reduced response is driven by insulin resistance, diabetic medications (some of which promote weight gain), and metabolic dysfunction that blunts the full effect of GLP-1 therapy

Dual-agonist medications like tirzepatide (Mounjaro) added GIP receptor activation to the equation, resulting in improved outcomes for many patients

The preclinical data demonstrates the mechanistic foundation, while existing human research on dihydroberberine's bioavailability and glucose metabolism effects provides additional validation