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These results prompted the hypothesis on a direct role of GLP-1 in controlling pubertal development through the hypothalamic GnRH secretion, although this mechanism still remains to be unraveled

Because of these broad effects, we wanted to see whether they would reduce all-cause mortality compared with another more weight-neutral diabetes medication. Mavromatis and colleagues conducted an observational study in which they used the Optum database to identify 170,030 adults (mean age, 56.8 years

Ultimately, the decision to start a GLP-1 should be made with a trusted healthcare professional who understands both the science and the unique challenges of menopause

doi: 10.1016/j.cmet.2013.04.008

[18] In March 2013, the FDA issued a Drug Safety Communication announcing investigations into incretin mimetics due to findings by academic researchers

Oral semaglutide versus empagliflozin in patients with type 2 diabetes uncontrolled on metformin: the PIONEER 2 trial