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glp-1 and alzheimer's disease Incretin insulin signaling as novel therapeutic targets for and Parkinson's Potential Role of Glucagon-like Peptide-1
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The recent positive topline results from Eli Lilly and Company 's ATTAIN-MAINTAIN trial for orforglipron, however, signal a potential paradigm shift
In support of this, ICV administration of GLP-1 in rats has been shown to attenuate the fasting-induced rise in NPY/AgRP expression and decreases fasting-induced inhibition of POMC/CART expression in the ARC (Seo et al., 2008)
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