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Though their use is supported by various professional guidelines, their injectable route of administration has been considered a barrier to widespread adoption

New emerging medications, including GLP1 receptor agonists, GIP receptor agonists, and glucagon receptor agonists, are beginning to approach weight loss levels that were previously only seen with bariatric surgery

From their beginnings as a treatment for type 2 diabetes, GLP-1 receptor agonists such as the semaglutide drugs Ozempic and Wegovy and the tirzepatide drugs Mounjaro and Zepbound have seen an explosion in use, most popularly for weight loss

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New research suggests that semaglutide (Wegovy), which is commonly used for weight loss, may reduce symptoms of heart failure in people with both type 2 diabetes and obesity