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The GLP-1 hormone is rapidly inactivated by the enzyme DPP-4, with a half-life of only 12 min

The subcutaneous route ensures gradual, sustained absorption into the bloodstream, which is essential for maintaining therapeutic drug levels and minimising side effects

[DOI] [PMC free article] [PubMed] [Google Scholar] 75.Salamone J.D., Correa M

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demonstrated that the high-dose liraglutide therapy was effective in increasing SHBG levels, while low-dose combination therapy resulted also in a decrease in total testosterone despite the minor effect on BMI [63]

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