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Mitochondrial calcium buffering capacity improves through regulation of the mitochondrial calcium uniporter (MCU), preventing calcium-induced mitochondrial dysfunction

Atherosclerosis 278 , 2938 (2018) Y
Cyndi Levine described her experience this way: I have more energy especially during that typical late afternoon slump

doi: 10.1152/ajpregu.1997.272.2.R726

Highlight cardioprotective mechanisms of action of GLP-1 agonist

Specifically, mutagenesis of ECD, ECL1 and ECL3 individually increased the basal activity of GCGR, which could result from the interruption of intramolecular interactions between the ECD and ECL1/3 that otherwise stabilize the receptor in an inactive state
