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By measuring TNF- and IFN- levels, inflammatory cytokines responsible for systemic inflammatory response, semaglutide was proved to lower them, thus, reduced the systemic inflammation

Agonists tickle and stimulate receptors in the brain, and this drug stimulates glucose-dependent insulin release from the pancreas

MeglutideIt is a GLP-1 receptor agonist with multiple effects
2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American college of cardiology/American heart association Task Force on practice guidelines and the obesity society

First and foremost, GLP-1 mediated signaling in the brain has a well-established neuroprotective effect, which has been repeatedly proven to enhance memory and cognitive functions, improve neurogenesis and synaptic functions, as well as restore balance in neurotransmission, i.e

If your provider sees your A1C and fasting glucose have dropped substantially since your last labs, this is expected and represents the therapeutic mechanism working as intended
