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In keeping with this, site-specific disruption of GLP-1R on neurons of the DMH of rats results in significant body weight gain paralleled by a reduction in energy expenditure and BAT heat production [777]
(2026, February 12)
Notably, the STEP TEENS trial showed that semaglutide 2.4 mg, administered once weekly via subcutaneous injection, can be used in individuals aged 12 years and older, as adolescents with obesity treated with semaglutide experienced a significant reduction in BMI compared with placebo, along with improvements in several cardiometabolic risk factors [47]
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Yarmolinsky and the other, anonymous, reviewer(s) for their contribution to the peer review of this work
