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Across patient records, the cough followed a recognizable pattern: Onset: Often developed weeks to months after starting GLP-1 therapy Duration: Frequently lasted longer than eight weeks, meeting criteria for chronic cough Clinical impact: Led to ENT referrals, reflux evaluations, asthma workups, and empiric treatments Clinical course: In some patients, cough-related visits decreased after stopping or switching therapy, although formal rechallenge data were limited Why Might GLP-1 Drugs Affect the Airway

David: Novozymes as well

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Beta cell GLP-1R signaling alters alpha cell proglucagon processing after vertical sleeve gastrectomy in mice

An engineered G s construct (mini-G s ) was used for expression and purification of the compound 2LY3502970GLP-1R complex, which was designed based on that used in the determination of A2AR-mini-G s crystal structure 48
