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Among the marketed large molecule injectable GLP-1 agonists, semaglutide, apart from weight-loss, is being studied for kidney disease and tirzepatide (a dual GLP-1 and GIP receptor agonist) is being evaluated for sleep apnea in Ph 3 clinical trials

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Adults with type 2 diabetes and cancer who used a GLP-1 had a lower risk for death and hospitalization compared with adults who used metformin, according to findings published in The Journal of Clinical Endocrinology &amp

In DIO mice treated with Semaglutide, weight loss attenuated, and body weight was maintained at a constant level after 2 weeks