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Now, heres a nuance thats going to come up, and this ones easy to miss

Utzschneider et al., 2020), a major question remains: Do SCFAs produced in the gut reach the pancreas in relevant concentrations to influence local receptors

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Clinical studies have shown that patients can expect significant weight loss (around 5-10% of their body weight) after about 6 months of consistent use, although individual results may vary based on lifestyle factors such as diet and exercise

Nutritional Priorities to support GLP-1 therapy for obesity: a joint Advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medecine Association, and The Obesity Society